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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: J Biomed Mater Res A. 2010 Dec 9;96(2):456–465. doi: 10.1002/jbm.a.32994

Table 1.

Molecular Weight and Polydispersity of Poly(amine-co-esters) and Characterization of Poly(amine-co-ester)/pLucDNANanoparticles

Substrates Isolated Polymer Properties of polyplexc
Diethyl Diester Diol Namea Mwb Mw/Mnb Mean Particle Diameters (nm) Zeta Potential (mV)
In NaAc In Hepes
Succinate N-Methyldiethanolamine PMSN 29500 2.3 620 8.7 −5.7
Adipate N-Methyldiethanolamine PMAP 29600 2.3 >1000 13.3 −20.6
Suberate N-Methyldiethanolamine PMSR 30300 2.4 >1000 20.7 −23.4
Sebacate N-Methyldiethanolamine PMSC 31800 2.3 69 35.4 −31.4
Dodecanedioate N-Methyldiethanolamine PMDO 41200 2.4 107 22.0 −26.2
Sebacate N-Ethyldiethanolamine PESC 29900 2.3 41 26.7 −23.9
Sebacate N-n-Butyldiethanolamine PBnSC 36000 2.2 880 10.4 −16.9
Sebacate N-t-Butyldiethanolamine PBtSC 44500 2.0 >1000 14.6 −15.3
Sebacate N-Phenyldiethanolamine PPSC 44200 2.2 724 11.3 −9.6
a

Abbreviations name of the polymers.

b

Molecular weight and polydispersity are cited from our previous work 44.

c

The polyplex nanoparticles were formed at polymer/DNA weight ratio of 100.