Table 2.

Prevalence and concurrence of proposed histological features of autoimmunity in 72 liver specimens from patients with ALF.

Histological Feature of AI-ALF	Type 4 or 5 Massive Hepatic Necrosis		Lymphoid Aggregates		Central Perivenulitis		Plasma Cell Enrichment
	Present N = 30	Absent N = 42	Present N = 23	Absent N = 49	Present N = 47	Absent N = 25	Present N = 45	Absent N = 27
Type 4 or 5 MHN (%)	--	--	65**	31	60†	8	60†	11
Lymphoid Aggregates (%)	50**	19	--	--	43**	12	42*	15
Central Perivenulitis (%)	93†	45	87**	55	--	--	100†	7
Plasma Cell Enrichment (%)	90†	43	83*	53	96†	0	--	--
Histological Diagnosis AI-ALF (%)	93†	33	83**	47	87†	4	87†	11

^*P≤0.05,

^**P < 0.01,

^***P < 0.001,

^†P < 0.0001 vs. “absent” group