Figure 3.
PKMζ blockade in the amygdala only disrupts memory at long retention intervals if rats are tested shortly after infusion. (a) Rats were infused with ZIP (n=7) or SCR ZIP (n=7) 1 day following training and tested 1 and 10 days later. (b) ZIP infusion caused a significant disruption (p < .05, t–test) of fear memory expression at both time points. Another set of rats were infused with ZIP (n=6) or SCR ZIP (n=8) and tested only at 10 days after infusion. No difference was seen between groups in those rats tested only at 10 days (b, right side).