Table 1.
Estimates of the LTNP and Δ32 Effects on Nucleotide Substitution Rates, Codon Substitution Rates, and dN/dS.
| Evolutionary Parameter | Effect Support/Size | LTNP Effect | Δ32 Effect |
| Nucleotide substitution rate | Posterior probability δeffect = 1 | 0.72 | 0.27 |
| BFeffect | 2.6 | 0.4 | |
| βeffect|δeffect = 1a | −0.275 (−0.524, −0.016) | −0.007 (−0.940,0.920) | |
| Codon substitution rate | Posterior probability δeffect = 1 | 0.726 | 0.324 |
| BFeffect | 2.6 | 0.5 | |
| βeffect|δeffect = 1a | −0.265 (−0.523,0.019) | −0.012 (−0.700,0.692) | |
| dN/dS | Posterior probability δeffect = 1 | 0.502 | 0.393 |
| BFeffect | 1.0 | 0.6 | |
| βeffect|δeffect = 1a | 0.083 (−0.101,0.25) | −0.005 (−0.228,0.242) |
a
These are effective sizes conditional on the effect being included (the binary effect indicator δeffect being 1). For the rates, these effective sizes are in log space. LTNP (Long-term non-progressor); Δ32 (CCR5 wt/Δ32).