Table 2.
Variables associated with death of persons with prevalent epilepsya
| All participants | Caseswith year of death ≥2004 | |||||||
|---|---|---|---|---|---|---|---|---|
| Controls (%) | Cases (%) | OR (95% CI) | P-value | Controls (%) | Cases (%) | OR (95% CI) | P-value | |
| Deprivation quintile | ||||||||
| 1 | 3236 (18) | 1967 (18) | Reference | 1653 (19) | 912 (19) | Reference | ||
| 2 | 3184 (18) | 1879 (17) | 1.00 (0.92 to 1.10) | 0.94 | 1523 (17) | 796 (17) | 1.01 (0.89 to 1.15) | 0.90 |
| 3 | 3525 (20) | 2075 (19) | 0.96 (0.89 to 1.05) | 0.41 | 1728 (19) | 959 (20) | 1.00 (0.88 to 1.13) | 0.99 |
| 4 | 3765 (21) | 2119 (20) | 0.93 (0.86 to 1.01) | 0.10 | 1842 (21) | 917 (19) | 0.93 (0.82 to 1.06) | 0.28 |
| 5 | 4175 (23) | 2741 (25) | 1.05 (0.97 to 1.14) | 0.27 | 2118 (24) | 1204 (25) | 1.03 (0.91 to1.15) | 0.68 |
| NK | 13 (0) | 16 (0) | 7 (0) | 11 (0) | ||||
| Alcohol-misuse problems | ||||||||
| No | 17 790 (99) | 10 585 (98) | Reference | 8815 (99) | 4704 (98) | Reference | ||
| Yes | 108 (1) | 212 (2) | 2.96 (2.25 to 3.89) | <0.001 | 56 (1) | 95 (2) | 2.71 (1.83 to 4.02) | <0.001 |
| Depression | ||||||||
| No | 16 093 (90) | 9212 (85) | Reference | 7865 (89) | 3970 (83) | Reference | ||
| Yes | 1805 (10) | 1585 (15) | 1.39 (1.28 to 1.50) | <0.001 | 1006 (11) | 829 (17) | 1.39 (1.25 to 1.56) | <0.001 |
| Injury/accident in previous 12 months | ||||||||
| No | 16 178 (90) | 9151 (85) | Reference | 8094 (91) | 4125 (86) | Reference | ||
| Yes | 1720 (10) | 1646 (15) | 1.41 (1.30 to 1.53) | <0.001 | 777 (9) | 674 (14) | 1.36 (1.20 to 1.53) | <0.001 |
| Time since last anticonvulsant prescription | ||||||||
| <90 days | 10 847 (61) | 8250 (76) | Reference | 5250 (59) | 3724 (78) | Reference | ||
| 91–182 days | 768 (4) | 1117 (10) | 1.83 (1.66 to 2.03) | <0.001 | 343 (4) | 429 (9) | 1.72 (1.47 to 2.01) | <0.001 |
| 183–365 days | 655 (4) | 437 (4) | 0.83 (0.72 to 0.94) | 0.004 | 278 (3) | 169 (4) | 0.77 (0.63 to 0.95) | 0.015 |
| ≥365 days | 5019 (28) | 908 (8) | 0.24 (0.22 to 0.26) | <0.001 | 2789 (31) | 426 (9) | 0.20 (0.18 to 0.23) | <0.001 |
| Never | 609 (3) | 85 (1) | 211 (2) | 51 (1) | ||||
| Recorded seizure free in previous 12 months | ||||||||
| No | – | – | – | – | 7135 (80) | 3771 (79) | Reference | |
| Yes | – | – | – | – | 1736 (20) | 1028 (21) | 0.78 (0.71 to 0.86) | <0.001 |
a
Figures are frequencies except where stated. Odds ratios were adjusted for each of the variables shown. NK = not known. OR = odds ratio.