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. 2011 Apr 18;193(2):307–318. doi: 10.1083/jcb.201012093

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© 2011 Dantas et al.

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Figure 5. — Hypersensitivity to UV irradiation of centrin-deficient cells and rescue by expression of centrins 4, 2, or 3. (A) Clonogenic survival assay of cells of the indicated genotype treated with the indicated doses of IR. Data points show mean ± SD of the surviving fractions in at least three separate experiments. (B) Clonogenic survival assay of cells of the indicated genotype treated with the indicated doses of UV-C irradiation. Data points show mean ± SD of the surviving fractions in at least three separate experiments. (C) Cetn4/2/3-deficient cells that were stably transfected with the indicated myc-centrin–expressing transgenes were analyzed by clonogenic survival assay. Survival curves show mean ± SD of the surviving fractions in at least three separate experiments.