Table 1.
Summary of study Characteristics
| ID | Authors | Year | Country | Design | Sample size | Inclusion and exclusion criteria | Study Quality (Jadad et al. Scores; SEQES) |
|---|---|---|---|---|---|---|---|
| 1 | Jarvik et al. [13] | 2009 | USA | RCT |
116 57( OCTR or ECTR) 59( Multi-modality* ) |
1. Clinical diagnosis of CTS greater than 2 weeks 2. Confirmed by electrodiagnostic studies 3. In absence of electrodiagnostic criteria, positive in night pain and flick test 4. Excluded if previous treatment with CTS release surgery, severe thenar muscle atrophy |
3/5 39/48 |
| 2 | Elwakil et al. [14] | 2007 | Egypt | Comparative cohort study |
60 30 (OCTR) 30 ( Laser ) |
Clinical diagnosis of CTS | 1/5 29/48 |
| 3 | Ucan et al. [15] | 2006 | Turkey | RCT |
57 11( OCTR) 23 ( Splinting ) 23 ( Splinting + one dose steroid injection) |
1. Mild to moderate clinical diagnosis of CTS greater than 6 months 2. Confirmed by electrodiagnostic studies 3. Excluded if advanced CTS, thenar atrophy or previous CTS treatment |
2/5 36/48 |
| 4 | Ly-Pen et al [16]. | 2005 | Spain | RCT |
163 80( OCTR) 83 (one or two-dose steroid injection ) |
1. Clinical diagnosis of CTS greater than 3 months 2. Confirmed by electrodiagnostic studies 3. Excluded if previous treatment with CTS release surgery, severe thenar muscle atrophy |
3/5 35/48 |
| 5 | Hui et al. [17] | 2005 | Hong Kong | RCT |
50 25( OCTR) 25 ( One dose steroid injection ) |
1. Clinical diagnosis of CTS greater than 3 months but less than 1 year 2. Confirmed by electrodiagnostic studies 3. Excluded if severe thenar muscle atrophy, ulnar, radial neuropathy |
3/5 38/48 |
| 6 | Demirci et al. [18] | 2002 | Turkey | Comparative cohort study |
90 44( OCTR) 46 ( Two-dose steroid injection ) |
1. Clinical diagnosis of CTS greater than 6 months 2. Confirmed by electrodiagnostic studies 3. Excluded if previous steroid injection, OCTR or distal radius fracture |
0/5 31/48 |
| 7 | Gerritsen et al [19] | 2002 | Netherlands | RCT |
176 87( OCTR) 89 ( Splinting ) |
1. Clinical diagnosis of CTS 2. Confirmed by electrodiagnostic studies 3. Excluded if severe thenar muscle atrophy |
3/5 40/48 |
RCT: randomized clinical trials
OCTR: standard open carpal tunnel release
ECTR: Endoscopic carpal tunnel release