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. 2011 Apr 20;6(4):e19102. doi: 10.1371/journal.pone.0019102

Figure 4. MUC1-CD promotes cellular proliferation of the mammary gland.

Figure 4

(A) Representative images of BrdU assays. BrdU was administered intraperitoneally to mice at 8 wks, 8.5 days and 13.5 days of pregnancy 2 h before sacrifice. Incorporated BrdU was detected in sections by IHC using an anti-BrdU antibody. Magnification: 400X. (B) The number of BrdU-positive epithelial cells in mammary lumina at 8 wks, pregnancy day 8.5 and pregnancy day 13.5 were counted. For each sample, cells were counted in 10 random high-power fields. Three mice were analyzed per group. The results are expressed as the percentage (mean±S.D.) of BrdU-positive cells. *P<0.05; **P<0.01; scale bars, 50 µm.