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Scheme Illustrating the Two Types of Adenylation (A) Domain Alterations Leading to New Substrate Specificities in Planktothrix spp.: Recombination of Whole Domains (McyAA1)9 or Shorter DNA Fragments (McyBA1)15 or Point Mutations (McyCA). C, condensation domain, NMT, N-methyl transferase, TE, thioesterase. Thick bars indicate the gene regions affected by mutation.
