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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Circ Cardiovasc Genet. 2011 Feb 15;4(2):179–187. doi: 10.1161/CIRCGENETICS.110.957662

Figure 1. Differences in AUC (ΔAUC) between placebo and dexmedetomidine infusions for different outcomes by haplotype 4.

Figure 1

Subjects homozygous for haplotype 4 (defined by rs553668) had a greater reduction in systolic BP (upper panel; adjusted P=0.006), diastolic BP (middle panel; adjusted P=0.007), and heart rate (lower panel; adjusted P=0.035) compared to carriers of 0 or 1 copy. Horizontal lines represent means, whiskers the standard error of the mean.