Table 1.
Comparison of the Intake, Tmax, Cmax, and AUC of plasma catechins after the i.g. administration of green teas (cv. Benifuuki)
| BGP 2.86 μm | BGP 18.6 μm | BGP 76.1 μm | BGI | |
|---|---|---|---|---|
| EGCG3”Me | ||||
| Intake (mg/rat) | 1.88 ± 0.05a | 1.81 ± 0.04ab | 1.74 ± 0.02b | 0.84 ± 0.04c |
| Tmax (h) | 1.57 ± 0.58 | 1.17 ± 0.09 | 1.85 ± 0.95 | 1.47 ± 0.10 |
| Cmax (μg/L) | 224.8 ± 98.9a | 40.5 ± 47.3b | 64.8 ± 40.6b | 74.5 ± 24.3b |
| AUC (μg h/L) | 760.9 ± 273.4a | 229.9 ± 152.3b | 319.8 ± 123.7b | 288.2 ± 112.6b |
| EGCG | ||||
| Intake (mg/rat) | 7.71 ± 0.15a | 7.46 ± 0.06a | 7.41 ± 0.05a | 3.60 ± 0.17b |
| Tmax (h) | 1.74 ± 0.57 | 2.89 ± 1.89 | 1.85 ± 0.88 | 2.76 ± 0.75 |
| Cmax (μg/L) | 642.7 ± 263.6a | 148.3 ± 97.1b | 739.3 ± 275.2a | 130.9 ± 63.4b |
| AUC (μg h/L) | 2763.5 ± 1158.9a | 968.3 ± 169.6b | 1157.7 ± 417.7b | 1166.4 ± 312.8b |
| ECG | ||||
| Intake (mg/rat) | 1.95 ± 0.04a | 1.88 ± 0.02a | 1.87 ± 0.01a | 0.80 ± 0.04b |
| Tmax (h) | 1.42 ± 0.09 | 2.87 ± 2.04 | 1.18 ± 0.62 | 2.11 ± 1.08 |
| Cmax (μg/L) | 171.2 ± 82.6a | 44.2 ± 34.2b | 79.4 ± 61.6a | 58.0 ± 24.5b |
| AUC (μg h/L) | 660.8 ± 191.9a | 305.2 ± 151.2b | 315.4 ± 150.9b | 222.1 ± 87.2b |
| EGC | ||||
| Intake (mg/rat) | 4.42 ± 0.09a | 4.30 ± 0.02a | 4.31 ± 0.04a | 3.75 ± 0.16b |
| Tmax (h) | 1.86 ± 0.61 | 1.55 ± 0.27 | 1.83 ± 0.93 | 1.47 ± 0.27 |
| Cmax (μg/L) | 903.1 ± 202.0 | 819.0 ± 251.0 | 757.6 ± 247.1 | 674.4 ± 213.1 |
| AUC (μg h/L) | 3577.0 ± 793.2 | 3447.5 ± 841.5 | 2887.0 ± 923.2 | 2463.2 ± 730.1 |
| EC | ||||
| Intake (mg/rat) | 1.38 ± 0.03a | 1.34 ± 0.02a | 1.33 ± 0.02a | 1.16 ± 0.05b |
| Tmax (h) | 1.83 ± 0.66 | 1.78 ± 0.75 | 1.83 ± 0.88 | 1.45 ± 0.28 |
| Cmax (μg/L) | 420.8 ± 148.2 | 571.2 ± 299.5 | 405.5 ± 168.3 | 479.9 ± 174.7 |
| AUC (μg h/L) | 1288.3 ± 315.7 | 1300.8 ± 462.3 | 1192.6 ± 839.9 | 1091.7 ± 443.0 |
All values represent the mean ± SD of 5 measurements except for the intake values (3 measurements)
EGCG3”Me, (-)-epigallocaetchin-3-O-(3-O-methyl) gallate; EGCG, (-)-epigallocatechin-3-O-gallate; ECG, (-)-epicatechin-3-O-gallate; EGC, (-)-epigallocatechin; EC, (-)-epicatechin. The catechin content was analyzed by HPLC with a binary gradient and ultraviolet visible detection (Intake) or a Coulochem-III electrode array system (Tmax, Cmax, and AUC). In each row, means with different superscript letters are significantly different, P < 0.05 (ANOVA and Tukey-Kramer’s method)