Table 1.

Incidence of diabetes in CD-1 mice treated with ERW and alloxan

Weeks after ALX administration	6th week			7th week			9th week			9th week
Blood sugar level (mg/dL)	150–350	>350	Death	150–350	>350	Death	150–350	>350	Death	>150
Control (n = 12)	2	4	1	5	5	2	2	7	3	100%
ERW (n = 12)	5	0	0	4	2	0	3	4	0	58.3%

Male ICR(CD-1 strain) mice were administrated ultrapure water (control) and ERW. At the 4th week time point, ALX was injected intraperitoneally 3 times and number of mice exhibiting abnormal blood sugar levels and dead mice were determined. Mice with basal glucose levels under the fasting condition ranging between 150 and 350 mg/dL were considered mild ALX-induced diabetic mice, and higher than 350 mg/dL were as severe ALX-induced diabetic mice. At 9th week, the incidence rate of mice exhibiting blood sugar levels more than 150 mg/dL were also shown