Table 3.
Variables | Significance univariate1 | Significance multivariate2 | Hazard ratio | 95% CI |
Overall survival | ||||
GLUT1 expression (< 50% vs ≥ 50%) | 0.047 | 0.534 | 1.101 | 0.813-1.491 |
Patient age (< 58 yr vs ≥ 58 yr) | < 0.001 | < 0.001 | 1.884 | 1.389-2.555 |
Differentiation (low vs high) | < 0.001 | < 0.001 | 1.846 | 1.344-2.536 |
AJCC stage (0, I, II vs III, IV) | < 0.001 | < 0.001 | 2.715 | 1.909-3.863 |
Vascular invasion (absent vs present) | 0.001 | 0.005 | 2.993 | 1.393-6.430 |
Disease free survival | ||||
GLUT1 expression (< 50% vs ≥ 50%) | 0.021 | 0.416 | 1.118 | 0.855-1.461 |
Patient age (< 58 yr vs ≥ 58 yr) | 0.002 | 0.003 | 1.497 | 1.150-1.947 |
Differentiation (low vs high) | < 0.001 | 0.002 | 1.593 | 1.193-2.126 |
AJCC stage (0, I, II vs III, IV) | < 0.001 | < 0.001 | 2.940 | 2.161-3.999 |
Vascular invasion (absent vs present) | 0.014 | 0.035 | 2.264 | 1.057-4.848 |
Log-rank test;
Cox proportional hazards model. GLUT1: Glucose transporter 1; CI: Confidence interval.