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. 2011 Apr 14;17(14):1895–1902. doi: 10.3748/wjg.v17.i14.1895

Figure 3.

Figure 3

MiR-622 promotes tumorigenesis and metastasis in vivo. A: Photographs of tumors in nude mice resulting from injection of miR-622 expression vector (pS-miR-622) or control plasmid (pS-control) stably transfected SGC-7901 cells; B: Tumorigenesis curves. Rapid tumor growth was observed in the pS-miR-622 group (data expressed as mean ± SD; P < 0.05); C: Photographs of the number of liver metastatic nodes in nude mice injected with pS-miR-622 or pS-control vector stably transfected SGC-7901 cells. The arrows indicate liver metastatic nodes; D: Histological examination found that the expression of ING1 was markedly reduced in the pS-miR-622-transfection group compared with the control groups. aP < 0.05, compared with miR-control transfectants. Scale bars: 200 μm. pS-control: Control plasmid; pS-miR-622: miR-622 expression vector.