Figure 2.
Regional plot for the chromosomes 9p21 (a) and 22q13 (b). Meta analysis log10 P values are plotted as a function of genomic position (Build 36). The P values for the lead SNPs are denoted by large blue (combined discovery and replication) diamonds. Proxies are indicated with diamonds of smaller size, with colours assigned based on the pairwise r2 values with the lead SNP in the HapMap CEU sample: red (r2>0.8), orange (0.5<r2<0.8) or yellow (0.2<r2<0.5). White indicates either no LD with the lead SNP (r2<0.2), or loci where such information was not available. Recombination rate estimates (HapMap Phase II) are given in light blue, Refseq genes (NCBI) in green.