Table 3.

Subgenual Cingulate Cortex Volumes of Medication-Based Groups

Descriptor	BD with Li and/or VPA (n = 10)		BD without Li or VPA (n = 10)		Healthy control group (n=20)
Regions of interest	Mean (cm3)	Standard deviation (cm3)	Mean (cm3)	Standard deviation (cm3)	Mean (cm3)	Standard deviation (cm3)	Group differences
Left anterior SGC gray matter volume	0.56	0.11	0.46	0.14	0.54	0.15	0.214
Left posterior SGC gray matter volume	0.28	0.06	0.21	0.04	0.22	0.06	0.008
Right anterior SGC gray matter volume	0.49	0.12	0.37	0.13	0.47	0.011	0.058
Right posterior SGC gray matter volume	0.28	0.08	0.22	0.05	0.23	0.07	0.044
Total posterior SGC gray matter volume	0.56	0.14	0.43	0.08	0.45	0.11	0.014
Total anterior SGC gray matter volume	1.05	0.20	0.83	0.26	1.00	0.24	0.206

SGC = subgenual cingulated cortex; BD = bipolar disorder; Li = lithium; VPA = valproate.