Table 8.
Genome scan of the MCTFR height data: SNPs reaching the Bonferroni corrected threshold
| Gene | Chromosome | SNP | Position, bp | p valuesa (×10−6) |
||||
|---|---|---|---|---|---|---|---|---|
| RFGLS-UN | RFGLS-VC | FGLS | GWAF | GEE | ||||
| NCOA1 | 2 | rsl7734306 | 24'575'942 | 0.4972 | 0.7124 | 0.6817 | 1.312 | 1.2393 |
| NCOA1 | 2 | rs2044148 | 24'591'337 | 0.5656 | 1.1625 | 0.7797 | 2.3934 | 1.6555 |
| NCOA1 | 2 | rs6720514 | 24'680'123 | 0.6306 | 0.8414 | 0.8785 | 1.6203 | 1.3927 |
| NCOA1 | 2 | rs2119115 | 24'740'285 | 1.0572 | 1.4161 | 1.4923 | (2.6626) | (2.1101) |
| ZBTB38 | 3 | rs13095453 | 142'557'652 | 1.7148 | 1.2829 | (2.0034) | 0.5056 | (92.0618) |
| ZBTB38 | 3 | rs6763931 | 142'585'523 | 0.7525 | 1.2135 | 0.8521 | 0.5958 | (32.7139) |
| ZBTB38 | 3 | rs6785073 | 142'622'020 | 0.1372 | 0.1982 | 0.1515 | 0.0904 | (4.0754) |
| – | 4 | rs7682418 | 105'647'866 | (6.2730) | 0.9890 | (7.6710) | (2.0177) | (2.2290) |
| – | 4 | rsl0516510 | 105'656'811 | 0.0175 | 0.0031 | 0.0168 | 0.0115 | 0.0003 |
| – | 4 | rs972583 | 105'661'751 | 0.0075 | 0.0015 | 0.0116 | 0.0055 | 0.0002 |
| – | 4 | rs17034592 | 105'674'409 | 0.0035 | 0.0009 | 0.0070 | 0.0025 | 0.0002 |
a
The Bonferroni corrected threshold is 1.9 × 10−6. p values in brackets are those not reaching the Bonferroni corrected significance level using the method presented, but reaching the threshold using any other method on the list.