Fig. 8.

A2bp1 is exclusively expressed in nonproliferating postmitotic zones. a A2bp1 is not expressed in the ganglionic eminence [medial (MGE), lateral (LGE)], but rather in the mantle at E12.5. b A2bp1-positive cells are evident in the mantle, the corticostriatal boundary, the lateral migratory stream (lms) and the cortical plate (CxP) at E13.5, which suggests that A2bp1 can be found in a variety of postmitotic cell types including striatal cells, tangentially migrating interneurons as well as cortical projection neurons. c A higher magnification view of the cortex at E13.5 shows A2bp1-positive cells along the medial surface of the cortex, at an age slightly before interneurons reach this area. d The presumptive projection neurons as well as some tangentially migrating interneurons in the dorsal pallium are darkly labeled as shown here at E15.5. The ventricular zone (VZ) contains undifferentiated A2bp1-negative cells, the subventricular zone (SVZ) contains A2bp1-positive cells that could be radially or tangentially migrating cells, the intermediate zone (IZ) contains some A2bp1-positive cells suggesting migrating interneurons and the subplate (SP) and cortical plate (CxP) contain A2bp1-positive cells, with the CxP containing the densest population of A2bp1-positive cells. The marginal zone (MZ) contains some A2bp1-positive cells (out of view). Scale bar = 200 μm.