Table 2.
Genetic differences between uncloned and biologically-cloned TAHV
| Nucleotide (amino acid) substitution in indicated segment | |||
|---|---|---|---|
| Virus | S | M | L |
| TAHV/58/CZ-cl(2)a | No changes | T1073A (F338I) | T673C |
| A1097G (N346D) | T2191C | ||
| T1110C (M350T) | T3664C | ||
| G1838A (E593K) | A5152G | ||
| C1846T | T5749A | ||
| T1920C (F630S) | G6533A (D2158N) | ||
| A1954C (K631N) | |||
| T2995C | |||
| TAHV/68/FR-clb | No changes | No changes | No changes |
| TAHV/84/CZ-clb | C729T | A2528G (K830E) | G1520T (D487Y) |
| T4468C | A2755G | ||
| C4469T | T4321C | ||
| G6820A | |||
| A6943T | |||
| C6945T | |||
a Genetic comparison between TAHV/58/CZ-cl(1) and TAHV/58/CZ-cl(2).
b Genetic comparison of uncloned parental virus and biologically cloned derivative.