Table 4.
Tahyna virus TAHV/58/CZ-cl(1) is immunogenic in rhesus monkeys in the absence of viremia
| Monkey Number | Peak virus titera (log10PFU/mL) | Neutralizing antibody titer on indicated dayb | |
|---|---|---|---|
| 0 | 42 | ||
| DBPN | <0.7 | <10 | 2673 |
| DBM6 | <0.7 | <10 | 1472 |
| A5E006 | <0.7 | <10 | 244 |
| DBXJ | 0.7 | <10 | 8379 |
| A5E036 | <0.7 | <10 | 1284 |
| L27 | <0.7 | <10 | 64 |
| L22 | <0.7 | <10 | <10d |
| DC11 | <0.7 | <10 | 701 |
| GMTc: | < 10 | 896 | |
a Serum was collected on days 0, 2, 4, 6, 8, 10, 14, 21, 28, and 42. Viremia was detectable only on day 4 in one monkey. Lower limit of detection is 0.7 log10PFU/mL.
b Reciprocal PRNT60 against TAHV/58/CZ-cl(1). Lower limit of detection is 10.
c Geometric mean neutralizing antibody titer.
d Monkey considered uninfected and PRNT not used in GMT calculation.