Table 1.
Explained Fraction of AIDS Restriction Genes (ARGs) for Progression to AIDS in 755 European American Seroconverter Subjects
| Locus | Variant | Model | Frequency, % | P | RH | EF (%) |
| CCR5 | Δ32 | D | 20.1 | .038 | 0.744 | 0.56 |
| CCR2 | 64I | D | 18.0 | .025 | 0.723 | 0.6 |
| SDF1 | 3'A | R | 3.4 | .061 | 0.488 | 0.5 |
| CCR5 | +/P1/+ haplotype | R | 12.4 | .001 | 1.667 | 1.18 |
| IL10 | 5'A | D | 41.9 | .170 | 1.165 | 0.2 |
| HLA B | B35Px | D | 8.4 | <.001 | 2.365 | 2.63 |
| HLA B | B27 | D | 9.8 | .002 | 0.513 | 1.65 |
| HLA B | B57 | D | 8.5 | .033 | 0.559 | 0.86 |
| HLA A, B, C | homozygosity at 1 gene | - | 22.6 | .664 | 1.067 | 0.03 |
| HLA A, B, C | homozygosity at 2 or 3 genes | - | 6.5 | .001 | 2.019 | 1.02 |
| RANTES | Haplotype 3 or 5 | D | 5.2 | .004 | 1.813 | 0.84 |
| KIR | 3DS1 | C | 21.8 | >.990 | 1 | 0 |
| KIR3DS1-HLA Bw480I | epistasis | - | - | .013 | 0.623 | 1.01 |
| PARD3B | G at rs11884476 | C | 6.3 | 3.370 × 10−9 | 0.29 | 4.52 |
| Combined ARGs | 15.6 |
NOTE. RH, relative hazard.