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. 2011 Apr 4;108(16):6543–6548. doi: 10.1073/pnas.1103471108

Fig. 5.

Fig. 5.

RNAi of the C. elegans histidyl tRNA synthetase gene hars-1 reduces fertility. hars-1 RNAi decreased the brood size of wild-type animals more dramatically than it did that of ced-4(n1162) animals, which have a defect in apoptosis. Eggs were collected from wild-type N2 or ced-4(n1162) adults on plates seeded with control or hars-1 RNAi bacteria and allowed to develop to the L4 stage. F2 progeny of 14 F1 animals exposed to control RNAi and 48 F1 animals exposed to hars-1 RNAi were counted. A representative experiment is shown. Error bars indicate SD.