Fig. 3.

Impact of cervical cytobrush T cell number on the magnitude of IFN-γ responses to PMA/Ionomycin. Cervical cells from HIV-infected women were assayed ex vivo for IFN-γ production in response to stimulation with PMA/Ionomycin. The number of cervical CD3⁺ T cell events captured in cytobrush samples that failed to respond (PMA−) or responded to PMA/Ionomycin (PMA+). Spearman Rank tests were used to test correlations while the Mann–Whitney U test was used to compare independent groups. P < 0.05 was considered significant.