Fig. 3.

TGF-β inhibits ADAMTS-4 protein expression in Hep3B cells. The cells were either left untreated (UT) or incubated with TGF-β for 48 h. Equal amounts of protein were subjected to Western blot analysis using antisera against ADAMTS-4 and the control β-actin, as indicated. The relative ADAMTS-4 expression normalised to β-actin, as determined by densitometric analysis, from three independent experiments is shown (mean ± SD) with the value from untreated cells arbitrarily assigned as 1 (*P < 0.05).