Fig. 2.

Helicase and RdRp phylogenetic trees of selected members of the family Flaviviridae. UPGMA phylogenetic trees of helicase and RdRp were generated using the alignments shown in Supplementary Figs S1 and S2, respectively. GenBank numbers for all isolates used in these analyses are provided in the legend for Supplementary Fig. S1. The node numbers represent the bootstrap values (expressed as a percentage of all trees) obtained from 2000 replicates. The tree was rooted by using the midpoint of the longest branch. A distance scale in amino acid substitutions per position is shown.