Table 1.
Comparison of tropism, host range and pathogenesis of GB viruses and Hepaciviruses
IDA, Insufficient data available; NWP, New World primates.
| Virus | Proposal* | Tropism | Host range | Pathogenesis |
|---|---|---|---|---|
| Pegivirus | ||||
| GBV-C | HPgV | Lymphocytes† | Humans, chimpanzee | None identified |
| GBV-Ccpz | SPgVcpz | ida | Chimpanzee | None identified |
| GBV-A | SPgV | Lymphocytes† | NWP | None identified |
| GBV-D | BPgV | ida | Bats | ida |
| Hepacivirus | ||||
| HCV | HCV | Hepatoctyes | Humans, chimpanzee | Hepatitis |
| GBV-B | GBV | Hepatocytes | NWP | Hepatitis |
*Genus (italics) and virus nomenclature proposed in this review.
†Data support lymphotropism, but other sites of replication are possible.