Fig. 9.
Mouse survival assay for Y. pestis KIM5 and individual deletion mutants. Overnight cultures of Y. pestis KIM5, KIM5 pCD1− and deletion mutants were intravenously inoculated into mice at a dose of 5–10 LD50 (∼50 bacteria). Mice were observed for 14 days after injection for survival. Ten mice were infected per day and the experiment was repeated once. Data are combined from the two experiments. Solid line, survival curve for KIM5; dashed line, survival curve of chaperone/usher mutant (given above each plot). P values were determined using logrank tests.