Table 5.
R2 and kidney size responses to l-NAME in the absence of ferumoxytol (group II-c, N = 4)
|
l-NAME results in absence of ferumoxytol |
ΔR2 in cortex [s−1] | ΔR2 in OSOM [s−1] | ΔR2 in ISOM [s−1] | Δarea |
| Response to l-NAME 1 | −1.9 ± 0.7 (p = 0.08) |
−1.9 ± 0.7 (p = 0.06) |
−1.0 ± 0.9 (p = 0.3) |
14 ± 5 % (p = 0.05) |
| Correlation between ΔR2 and Δarea | r = −0.974* (p = 0.03) |
r = −0.988* (p = 0.012) |
r = −0.965* (p = 0.03) |
1
Response to l-NAME = mean [(acquisition 7) and (acquisition 8)] – mean [(acquisition 1) to (acquisition 3)]; refer to Figure 5 for acquisition timing
*
significant (p < 0.05)
All results expressed as mean ± SEM