Figure 2.

Effect of NP- 313 on aggregation of washed human platelets. Washed human platelets were incubated with DMSO (vehicle control) or NP-313 at 37°C for 3 min, and then collagen (10 µg·mL⁻¹), arachidonic acid (AA; 200 µM), thapsigargin (0.1 µM), thrombin (0.1 U·mL⁻¹) or A23187 (8 µM) was added to trigger platelet aggregation. Data are presented as the mean ± SEM (n = 5).