Table 2.
Cellular Distribution of Oncostatin M In Bone Marrow Sections in Mastocytosis and Controls
| Cell type | Normal BM | ISM | MCL | SM-AHNMD |
|---|---|---|---|---|
| Megakaryocytes | ++ | ++ | ++ | ++ |
| Myeloid progenitors | + | + | + | + |
| Neutrophil granulocytes | − | − | − | − |
| Eosinophil granulocytes | − | − | − | − |
| Erythroid progenitors | − | − | − | − |
| Mast cells | ND⁎ | + | + | + |
| Endothelial cells | + | + | + | + |
| Endosteal cells | + | + | + | + |
BM, bone marrow; ISM, indolent systemic mastocytosis; MCL, mast cell leukemia; ND, no data; SM-AHNMD, systemic mastocytosis with associated clonal hematologic non-mast cell lineage disease; −, negative; +, positive; ++, strongly reactive.
Bone marrow sections were stained with an antibody against oncostatin M as described under Materials and Methods.
⁎
Only a few diffusely spread mast cells were found in normal bone marrow.