Table 1.
Average Body Weight and Blood Glucose Concentration Assessed at Different Time Points
| Average body weight, g |
Average blood glucose concentration, mg/dL |
|||||
|---|---|---|---|---|---|---|
| Time after vehicle or streptozotocin injection | Control | Diabetes without ischemia pulses | Diabetes with ischemia pulses | Control | Diabetes without ischemia pulses | Diabetes with ischemia pulses |
| 3 days | 315.6 ± 9.4 | 337.6 ± 10.0 | 333.7 ± 8.4 | 109.4 ± 6.4 | 484.7 ± 16.5⁎ | 476.0 ± 15.4⁎ |
| 3 weeks | 404.3 ± 5.1 | 320.0 ± 7.9⁎ | 305.4 ± 5.2⁎ | 110.3 ± 4.3 | 498.1 ± 12.7⁎ | 502.3 ± 12.9⁎ |
| 6 weeks | 432.6 ± 4.7 | 317.2 ± 11.1⁎ | 306.7 ± 12.2⁎ | 105.9 ± 5.3 | 519.8 ± 16.5⁎ | 528.3 ± 16.2⁎ |
| 10 weeks | 461.2 ± 6.1 | 307.8 ± 19.2⁎ | 300.6 ± 18.5⁎ | 117.5 ± 4.3 | 583.4 ± 9.8⁎† | 596.3 ± 8.3⁎† |
The injection of streptozotocin induced a significant decrease in body weight and an increase in blood glucose levels. Ischemia pulses in streptozotocin-injected rats did not change these parameters. Data are given as mean ± SEM (n = 10 animals per group). No significant differences in the average body weight were observed in diabetic animals during the study.
⁎
P < 0.01 versus aged-matched control animals, by Tukey's test.
†
P < 0.01 versus 3 days after streptozotocin injection, by Dunnett's test.