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. 2011 May;127(5):e1288–e1295. doi: 10.1542/peds.2010-0938

Table 4.

Factors Associated with Risks/Benefits and Willingness to Consider Genetic Testing for Children

Variable β SE of β t P
Decisional balance; R2 = 0.33, P < .0001
    Parent gender 0.08 0.06 1.22 .23
    Child age 0.00 0.01 0.12 .91
    Perceived risk to child* −0.04 0.03 −1.63 .11
    Child behavior change intentions 0.02 0.05 0.44 .66
    Knowledge of gene-health relationships −0.10 0.04 −2.81 .006
    Knowledge of behavior-health relationships −0.03 0.04 −0.86 .39
    Difficulty learning predictive genetic health information 0.05 0.02 3.21 .002
    Positive reactions to decreased risk −0.07 0.02 −3.02 .003
    Intention to undergo genetic testing −0.07 0.07 −1.00 .32
Willingness to consider child genetic testing; R2 = 0.59, P < .0001
    Parent gender −0.50 0.20 −2.49 .01
    Child age 0.01 0.02 67 .50
    Perceived risk to child* 0.21 0.08 2.60 .01
    Child behavior change intentions −0.03 0.16 −0.21 .84
    Knowledge of gene-health relationships 0.54 0.11 4.79 <.0001
    Knowledge of behavior-health relationships −0.18 0.12 −1.53 .13
    Difficulty learning predictive genetic health information −0.19 0.05 −3.82 .0002
    Positive reactions to decreased risk −0.17 0.07 −2.34 .02
    Intention to undergo genetic testing 0.58 0.21 2.79 .006
    Decisional balance −1.52 0.23 −6.51 <.0001
*

Averaged across 8 health conditions (colon, skin, and lung cancer; heart disease; osteoporosis; high blood pressure; high cholesterol; and type 2 diabetes).