Table 1.
Summary of Clinicopathological Features of 98 Patients
| Parameters | Number of cases (%) |
|---|---|
| Sex | |
| Male | 97 (99.0%) |
| Female | 1 (1.0%) |
| Age (years) (Median, 68; range, 34–87) | |
| ≤40 | 20 (20.4%) |
| 41–50 | 35 (35.7%) |
| 51–60 | 30 (30.6%) |
| 61–70 | 10 (10.2%) |
| 71–80 | 3 (3.1%) |
| 81–90 | 1 (1.0%) |
| Tumor location | |
| Tongue | 40 (40.8%) |
| Buccal | 37 (37.8%) |
| Others | Lip (6), mouth floor (6), palate (5), trigone (4) |
| Primary tumor (T) | |
| T1 | 18 (18.4%) |
| T2 | 31 (31.6%) |
| T3 | 17 (17.3%) |
| T4 | 32 (32.7%) |
| Nodal status (N) | |
| N0 | 38 (46.3%) |
| N1 | 14 (17.1%) |
| N2 | 30 (36.6%) |
| Nx | 16 |
| Extracapsular extension of metastatic nodes | |
| Present | 32 (61.5%) |
| Absent | 20 (38.5%) |
| Histological grade | |
| Well differentiated | 61 (62.2%) |
| Moderately differentiated | 29 (28.6%) |
| Poorly differentiated | 9 (9.2%) |
| Vascular invasion | |
| Present | 18 (18.4%) |
| Absent | 80 (81.6%) |
| Perineurial invasion | |
| Present | 26 (26.5%) |
| Absent | 72 (73.5%) |
| Tumor necrosis | |
| Present | 38 (38.8%) |
| Absent | 60 (61.2%) |
| CIS at adjacent mucosa | |
| Present | 24 (24.5%) |
| Absent | 74 (75.5%) |
| Surgical margin | |
| Clear (≥5 mm) | 91 (94.8%) |
| Unclear | 5 (5.2%) |
| Not assessable | 2 |
| RSF-1 expression | |
| Low expression (0+∼2+) | 44 (44.9%) |
| Overexpression (3+∼4+) | 54 (55.1%) |
CIS, carcinoma in situ.