TABLE 1.
BASELINE CHARACTERISTICS OF PATIENTS*
| Pulmonary Hypertension | Control Subjects | |||
|---|---|---|---|---|
| Etiology | Age | 36 ± 19 | ||
| IPAH | 5 | Sex | ||
| Sarcoid | 1 | M | 2 | |
| EtOH | 1 | F | 2 | |
| Rheumatic | 1 | |||
| Congenital | 1 | Cause of death | Head trauma | |
| Drug induced | 1 | |||
| IPAH | Non-IPAH | |||
| Age | 43 ± 14 | 48 ± 15 | ||
| Sex | ||||
| M | 2 | 1 | ||
| F | 3 | 4 | ||
| Echocardiographic, mm Hg | ||||
| RVSP | 130 ± 49 | 95 ± 16 | ||
| LVEF | >50% | 10–50% | ||
| Hemodynamic, mm Hg | ||||
| PA mean | 59 ± 17 | 49 ± 10 | ||
| PCWP | 7 ± 3 | 18 ± 5 | ||
| Six-minute walk, ft | 1010 ± 295 | 1000 ± 95 | ||
| Therapy | ||||
| Flolan | 2 | 2 | ||
| Remodulin | 1 | |||
| Flolan, Bosenan | 1 | 1 | ||
| Flolan, Sildenafil | 1 | |||
| None | 1 | 1 | ||
Definition of abbreviations: EtOH = ethanol; IPAH = idiopathic pulmonary arterial hypertension; LVEF = left ventricular ejection fraction; PA = pulmonary arterial; PAP = pulmonary arterial pressure; PCWP = pulmonary capillary wedge pressure; RVSP = right ventricular systolic pressure.
*
Lung tissue samples were examined from four normal control subjects and compared with five patients with PAH and five with other forms of PH.