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. 2010 Oct 1;183(5):659–667. doi: 10.1164/rccm.201007-1027OC

TABLE 3.

ASSOCIATIONS BETWEEN BIOAVAILABLE TESTOSTERONE AND RIGHT VENTRICULAR MEASURES IN LIMITED AND ADJUSTED MODELS, BY SEX

Men (n = 1,925)
Women (n = 1,696)
β (95% CI)* P Value β (95% CI) P Value
RVEF, %
 Limited −0.37 (−0.97 to 0.23) 0.23 −0.15 (−0.51 to 0.20) 0.40
 Adjusted −0.36 (−0.95 to 0.24) 0.25 −0.01 (−0.38 to 0.36) 0.97
 Adjusted + LVEF −0.40 (−0.94 to 0.14) 0.15 0.02 (−0.33 to 0.37) 0.92
RVSV, ml
 Limited 1.42 (−0.37 to 3.21) 0.12 −0.66 (−1.47 to 0.14) 0.11
 Adjusted 1.97 (0.20 to 3.73) 0.03 −0.04 (−0.88 to 0.79) 0.92
RV mass, g
 Limited 0.40 (0.03 to 0.76) 0.03 −0.03 (−0.20 to 0.15) 0.77
 Adjusted 0.49 (0.13 to 0.85) 0.01 0.08 (−0.10 to 0.26) 0.38
 Adjusted + LV mass 0.44 (0.10 to 0.77) 0.01 0.04 (−0.13 to 0.21) 0.66
RVEDV, ml
 Limited 2.90 (0.47 to 5.33) 0.02 −0.70 (−1.75 to 0.36) 0.20
 Adjusted 3.71 (1.31 to 6.11) 0.001 −0.05 (−1.15 to 1.06) 0.93
 Adjusted + LVEDV 2.43 (0.64 to 4.21) 0.01 0.13 (−0.69 to 0.94) 0.78
RVESV, ml
 Limited 1.48 (0.26 to 2.70) 0.02 −0.03 (−0.55 to 0.49) 0.91
 Adjusted 1.74 (0.53 to 2.96) 0.01 −0.01 (−0.55 to 0.54) 0.98
 Adjusted + LVESV 1.63 (0.55 to 2.71) 0.001 −0.01 (−0.51 to 0.49) 0.96

Definition of abbreviations: CI = confidence interval; LV = left ventricle; LVEDV = left ventricular end-diastolic volume; LVEF = left ventricular ejection fraction; LVESV = left ventricular end-systolic volume; RV = right ventricle; RVEDV = right ventricular end-diastolic volume; RVEF = right ventricular ejection fraction; RVESV = right ventricular end-systolic volume; RVSV = right ventricular stroke volume.

*

Per ln(nmol/L) increase in bioavailable testosterone.

Adjusted for age, race/ethnicity, height, weight, waist circumference, and testosterone supplementation (in men).

Adjusted for age, race/ethnicity, height, weight, waist circumference, testosterone supplementation (in men), smoking (status and pack-years), diabetes mellitus, impaired glucose tolerance, hypertension, use of antihypertensive medications, systolic and diastolic blood pressure, cholesterol, high density lipoprotein levels, statin use, intentional exercise, and level of education.