TABLE 1.
CLINICAL CHARACTERISTICS OF THE 23 STUDY SUBJECTS
| Subject Characteristic | Patients with COPD (n = 11) | Control Subjects (n = 12) | P Value (unpaired t test) |
|---|---|---|---|
| Age, yr | 59.6 (47–70) | 48.5 (40–58) | 0.0021 |
| Sex, M/F | 6/5 | 6/6 | NS |
| Smoking history, pack-years* | 48 (20–109) | 34.8 (20–60) | NS |
| Current smokers, no. | 8 | 9 | NS |
| FEV1, L | 1.94 (1.23–2.7) | 3.58 (2.8–4.76) | <0.0001 |
| FEV1, % of predicted normal value | 69.73 (62–78) | 109.5 (90–128) | <0.0001 |
| FEV1/FVC, % | 55.55 (39–69) | 80.33 (73–86) | <0.0001 |
Definition of abbreviations: COPD = chronic obstructive pulmonary disease; F = female; M = male; NS = not significant.
Values are presented as means (range).
*
Pack-years, the number of cigarettes smoked per day multiplied by the number of years of smoking.