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. 2011 Apr 22;6(4):e17887. doi: 10.1371/journal.pone.0017887

Table 3. The area and property of the interfaces in the Fab/antigen complexes.

Interface bH1/VEGF bH1/HER2 Hercepin/HER2
bH1 VEGF Combined Fraction bH1 HER2 Combined Fraction Herceptin HER2 Combined Fraction
Polar 311 295 606 40% 308 282 591 37% 307 308 614 40%
Apolar 438 462 900 60% 470 518 988 63% 441 469 910 60%
Total 749 757 1506 779 800 1579 747 777 1524

All numbers in Å2 unless otherwise indicated.

The polar and apolar area of the interfaces was assessed using XSAE (See Methods). The area was calculated using a probe with a radius of 1.4 Å.