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. 2011 Apr 22;6(4):e17626. doi: 10.1371/journal.pone.0017626

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Burghaus et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Rivaroxaban concentrations at 20 mg once daily: C_max 251 ng/ml, C_trough 30 ng/ml. The width of the rivaroxaban curve reflects the C_trough to C_max concentration range and the width of the warfarin curve reflects the typically used INR range. C_max, maximum concentration; C_trough, minimum concentration; INR, international normalized ratio; OD, once daily; TF, tissue factor.