Uptake of radioactivity. Uptake of radioactivity per tissue (Bq) after A) Bip-125I-35A7-RIT or B) iv-125I-35A7-RIT, was determined using the values obtained during the biodistribution experiments (see Figure 5). For clarity, only the most representative results are shown and uptake values out of scale (0—1.5×106 Bq) are shown in Suppl. Fig. 6A and 6B. C) Mean absorbed irradiation dose for Bip-125I-35A7-RIT and iv-125I-35A7-RIT. From uptake of radioactivity curves, the total cumulative decay per tissue, Ãrs, was calculated by calculating the area under each curve. Ãrs was then multiplied by 19.483 keV, which corresponds to the mean energy delivered at each 125I decay.