Figure 9. Survival of mice inoculated with F. tularensis LVSΔ1423/1422.
Groups of BALB/c mice were inoculated IN (A) or IP (B), and survival was monitored for six weeks. No mice challenged IN with LVSΔ1423/1422 died during the study. The doses and symbols used for IN inoculations were about 1.2×104 CFU/mouse of LVS (•), and about 1.6×104 CFU of LVSΔ1423/1422 (▴). The doses and symbols used for IP inoculations were 262 CFU/mouse of LVS (•); 3,375 CFU/mouse of LVS (x); 1,124 CFU/mouse of LVSΔ1423/1422 (▴); 11,136 CFU/mouse of LVSΔ1423/1422 (♦); 33,408 CFU/mouse of LVSΔ1423/1422 (▪).