Figure 5. Distinct genetic events in WT.

In (A) a small deletion is observed on chromosome 3p in GOS 536 which defines the MRO for losses on this chromosome. In (B) loss of 7p and gain of 7q (iso-7q) in GOS 21 reflects a common event in WT. The CNN LOH event in GOS 439 (C) involves a small region on 9q which defines the MRO for losses in this series of WT. The overlapping deletions on chromosome 14 in GOS 358 (D) and GOS 407 (E) define the MRO of losses on this chromosome.