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. 2011 Apr 22;6(4):e19094. doi: 10.1371/journal.pone.0019094

Figure 3. Clustering of human GPCRs.

Figure 3

In (A), the histograms show the distribution of the receptors from groups G0 (black bars), G1 (white bars), G2 (grey bars) and G3 (hatched bars) as a function of their coordinates on the first, second and third components (from top to bottom). In (B), the four clusters obtained by K-means analysis are visualized by spanning ellipses onto the plane formed by the first two components. The insert displays the Silhouette score S obtained for K-means clustering as a function of the number of clusters. The color code refers to the GPCR sub-families (AD: brown; AMIN: light blue; CHEM: dark blue; LGR: yellow; MEC: pink; MTN: grey; MRG: violet; OPN: orange; PEP: dark green; PTG: cyan; PUR: light green; SO: red; UC: black).