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. 2011 Apr 22;6(4):e19094. doi: 10.1371/journal.pone.0019094

Figure 6. Projection of GPCRs from non-human sub-families onto the sequence space of human GPCRs.

Figure 6

GPCRs from N. vectensis (A) or C. elegans (B) that cannot be attributed to sub-families present in humans are projected onto the plane formed by the first two components of the human active space. Projected elements (397 and 47 sequences from N. vectensis and C. elegans, respectively) are represented by black dots. Transparent circles represent human elements. Their color code refers to the GPCR sub-families (AD: brown; AMIN: light blue; CHEM: dark blue; LGR: yellow; MEC: pink; MTN: grey; MRG: violet; OPN: orange; PEP: dark green; PTG: cyan; PUR: light green; SO: red; UC: black). The ellipses indicate the positions of the human G0 receptors.