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. 2011 Apr 22;6(4):e19204. doi: 10.1371/journal.pone.0019204

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Skuginna et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Cortical renal sections were stained with silver. Images illustrate representative sections of UUO and sham-operated kidneys 10 days after UUO in mice of the respective group as indicated (original magnification 200×). The indices for interstitial volume, tubular damage, and tubular lumen were determined in UUO kidneys from wildtype (black bars) and Sigirr-deficient mice (white bars) by quantitative morphometry as decribed in the methods section. Values represent means ± SD from 10 high power fields of UUO kidneys from 10 mice in each group.