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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Brain Behav Immun. 2010 Dec 30;25(4):604–615. doi: 10.1016/j.bbi.2010.12.017

Fig. 3. MIA activates decidual leukocytes to express CD69.

Fig. 3

A. Compared to controls, placentas from poly(I:C)-injected mothers harbor increased numbers of CD69-expressing CD11b+, Gr-1+ and DBA lectin+ cells [F(1,12)=24.76, ***p=0.0003; n=5 litters per treatment group (7-8 deciduas pooled per litter)]. These are similarly increased in poly(I:C)-injected IL-6-/- mothers, suggesting that this effect occurs independently of IL-6 action [F(1,12)=21.87, **p=0.0005]. B. Representative flow cytometry spectra show increased total CD69+ cells in poly(I:C) decidual suspensions (left) and increased CD69+ CD11b+ cells from a non-erythroid parent population (right) C. Increased activation of decidual leukocytes corresponds with a trending increase in total CD69+ gene expression (# p = 0.08; n=9 placentas per treatment group (pooled from 3 independent litters)