Table 2.
SNP | Trait | p-value | n | Standardized Effect Size |
Variance explained |
Effect Allele |
Effect Allele Freq |
|
---|---|---|---|---|---|---|---|---|
B | SE | |||||||
rs1367117 | ApoB | 6.83×10−06 | 2250 | 0.146 | 0.032 | 0.90% | A | 0.27 |
LDL-C* | 6.06×10−03 | 1551 | 0.107 | 0.039 | 0.49% | |||
TC | 2.07×10−05 | 2384 | 0.135 | 0.032 | 0.76% | |||
rs7575840 | ApoB | 3.33×10−05 | 2272 | 0.134 | 0.032 | 0.76% | T | 0.28 |
LDL-C | 2.2×10−02 | 1563 | 0.089 | 0.039 | 0.34% | |||
TC | 9.65×10−05 | 2406 | 0.123 | 0.031 | 0.63% | |||
rs693 | ApoB | 2.90×10−06 | 2312 | 0.140 | 0.030 | 0.94% | A | 0.37 |
LDL-C | 3.86×10−03 | 1598 | 0.103 | 0.036 | 0.52% | |||
TC | 6.41×10−05 | 2446 | 0.116 | 0.029 | 0.65% |
Linear regression was performed in the Mexican study sample using an additive model, as described in the footnote to Table 1.
Serum LDL-C levels were calculated using the Friedewald formula only for subjects with TGs<400 mg/dL.