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. Author manuscript; available in PMC: 2012 May 1.
Published in final edited form as: Dev Dyn. 2011 Feb 28;240(5):1142–1150. doi: 10.1002/dvdy.22583

Fig. 3.

Fig. 3

Hindlimb induction and patterning occurs normally in Rdh10trex/trex mutant embryos. In situ hybridization of hindlimb induction and patterning genes at E9.5 and E10.5 reveals no difference between wild-type and mutant. (A–B) E9.5; Tbx4 representing the early hindlimb (arrows) and Uncx4.1 marking the somites. (C–D) E10.5; Fgf8 expression distally in hindlimb AER. (E–F) E10.5; Meis2 expression in the proximal hindlimb bud region (arrowheads). (G–H) E10.5; Shh expression posteriorly in the hindlimb ZPA.