Figure 2.

B6 Congenic Mice Deficient in CD94 Are Susceptible to Mousepox

(A) Flow cytometry analysis of white blood cells in B6.D2-D6 mice. Top: Gated on lymphocytes according to forward angle (FSC) and side angle (SSC) light scattering properties. Staining for NKp46 and CD3 is shown. Bottom: gated on NKp46⁺CD3⁻ (NK) cells as indicated in the upper plots. Staining for CD94 and NKG2 is shown.

(B) Wild-type B6, CD69-deficient, and CD94-deficient mice were infected with ECTV and survival was monitored. p value for wild-type B6 or CD69-deficient versus CD94-deficient mice.

(C) Virus titers in spleen and liver 7 dpi (gray columns, B6 mice; white columns, CD94-deficient mice).

Data correspond to the average ± SD of six individual mice from two independent experiments.