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. 2011 Mar 6;49(3):221–229. doi: 10.1007/s10858-011-9481-9

Table 4.

Isotopomer distribution of glutamate in RBCs incubated with [13C1,2,3,4] α-ketoglutarate, alanine, and glucose

Time (h) Percent Mass isotopomer distribution (glutamate)a
Monoisotopic M + 1 M + 2 M + 3 M + 4
0 95.3 ± 1.7 4.66 ± 1.66 0 0 0
6 15.9 ± 0.7** 0.72 ± 0.08** 0.10 ± 0.10 2.52 ± 0.37* 80.8 ± 0.3**
12 10.4 ± 0.7** 0.41 ± 0.01** 0 3.08 ± 0.55* 86.1 ± 0.9**
21.25 7.47 ± 0.24** 0.24 ± 0.01** 0 2.82 ± 0.14* 89.4 ± 0.3**
Expected distribution due to natural abundance 93.40 5.64 0.91 0.05 0.00

aMeans and S.E.M. for n = 3

p < 0.05; ** p < 0.001