Table 2.
Controls groups | Cryptorchid groups | ||||||
---|---|---|---|---|---|---|---|
Control | Sham-Vehicle | Sham αT-30 | Sham αT-100 | Vehicle | αT-30 | αT-100 | |
Testis weight (g) | 1.84 ± 0.063† | 1.78 ± 0.056† | 1.80 ± 0.017† | 1.90 ± 0.035† | 1.28 ± 0.096* | 1.61 ± 0.028 | 1.49 ± 0.142*‡ |
HI | 0.25 ± 0.04† | 0.33 ± 0.05† | 0.31 ± 0.04† | 0.27 ± 0.05† | 3.08 ± 0.21* | 0.92 ± 0.08*† | 1.49 ± 0.11*†‡ |
EA (μm2) × 103 | 79.91 ± 1.10† | 74.75 ± 8.94† | 74.73 ± 8.41† | 74.51 ± 8.24† | 45.71 ± 2.76* | 75.22 ± 1.57† | 68.93 ± 0.82*†‡ |
AI | 1.00 ± 0.13† | 1.19 ± 0.12† | 1.08 ± 0.11† | 0.53 ± 0.04† | 3.24 ± 0.26* | 1.07 ± 0.11† | 1.48 ± 0.16† |
PI | 12.21 ± 1.64 | 11.68 ± 1.78† | 12.65 ± 1.21† | 15.71 ± 1.14 | 10.0 ± 1.21 | 12.67 ± 1.33 | 11.68 ± 1.78 |
JI | 10.0 ± 0† | 9.74 ± 0.09† | 9.93 ± 0.25† | 10 ± 0.01† | 8.43 ± 0.38* | 9.83 ± 0.07† | 9.74 ± 0.07† |
Spermatocytes and spermatids number (×106) | 82.64 ± 5.52† | 78.37 ± 14.44† | 71.20 ± 1.48† | 78.41 ± 2.91† | 34.30 ± 3.67* | 60.51 ± 3.98 | 51.52 ± 2.44* |
Pregnant female/total evaluated female | 12/12† | 8/12† | 10/12† | 12/12† | 2/12* | 6/12 | 5/12* |
The data were collected from six animals by group and are expressed as the mean ± SEM.
αT, α-tocopherol; TBARS, thiobarbituric acid-reactive substances; HI, histopathological index; EA, epithelial area; AI, apoptosis index; PI, proliferation index; JI, Johnsen index.
P < 0.05 (vs. control).
P < 0.001 (vs. cryptorchid-vehicle).
P < 0.001 (cryptorchid-αT-30 vs. cryptorchid-αT-100).